李　想：教授，博士，植物科学学院。

　　个人简历

　　2002年7月吉林农业大学博士毕业后进入北京大学天然药物与仿生药物国家重点实验室进行博士后研究工作。

　　2004年10月获得BMBF奖学金赴德国汉斯-可奈天然产物研究所（HKI）做访问学者；

　　2005年获得DAAD奖学金赴德国杜塞尔多夫大学进行访问研究；

　　2006年10月至2009年10月获得NSERC奖学金在加拿大农业部萨斯卡通研究所进行博士后研究。

　　2010年1月入选“2009年新世纪优秀人才支持计划”回国工作，现为吉林大学植物科学学院教授，博士生导师，吉林大学药用植物生物技术方向学术带头人。为北美植物学会、化学学会会员，加拿大农业部萨斯卡通研究中心客座研究员。

　　联系方式

　　电子信箱： li_xiang@jlu.edu.cn

　　社会职务

　　Organic and Medicinal Chemistry Letters 》和《 Research in Pharmaceutical Biotechnology 》杂志编委，《 Bioresource Technology 》等杂志评审专家。

　　招生学科

　　博士招生学科： 植物学

　　硕士招生学科： 植物学、农药学

　　研究方向

　　天然产物生物合成与调控、 农药合成与应用

　　代表性课题

　　2009 年新世纪优秀人才支持计划（NCET-09-0423 ，教育部，主持人）

　　项目名称：中药虎杖中白藜芦醇的生物合成研究

　　主要内容：克隆中药虎杖中白藜芦醇的生物合成基因，其中包括结构基因：白藜芦醇合酶 STS ，肉桂酸途径合成基因 PAL ， C4H 和 4CL ；在融合超表达该系列基因的同时，通过调控木质素生物合成的转录因子如 R2R3-MYB 等，提高白藜芦醇前体化合物的含量，从而整体提高虎杖中白藜芦醇的含量。

　　论文著作

　　• Li, Xiang* ; Gao, Peng; Wu, Limin; Cui, Dejun; Parkin, Isobel; Saberianfar, Reza; Menassa, Rima; Pan, Hongyu; Westcott, Neil; Gruber, Margaret Y * . The Arabidopsis tt19-4 mutant differentially accumulates flavonoids, proanthocyanidins and anthocyanin through a 3' amino acid substitution in glutathione S -transferase. ( Plant Cell & Environment : doi:10.1111/j.1365- 3040.2010.02249.x, (2010); *Corresponding author)

　　• Qin, Jianchun; Zhu, Lin; Gao, Mingjun; Wu, Xian; Pan, Hongyu; Zhang, Yansheng*; Li, Xiang * . Cloning and functional characterization of a chalcone isomerase from Trigonella foenum-graecum L. ( Planta Medica : doi:10.1055/s-0030-1250566, (2010), *Corresponding author)

　　• Li, Xiang ; Westcott, Neil; Links, Matthew; Gruber, Margaret Y. Seed coat phenolics and the developing silique transcriptome of Brassica carinata . ( Journal of Agricultural and Food Chemistry , 58 (2010), 10918 – 10928)

　　• Qin, Jianchun; Su, Hua; Zhang, Yamei; Gao, Jinming; Zhu, Lin; Wu, Xian; Pan, Hongyu*; Li, Xiang * . Highly brominated metabolites from marine red alga Laurencia similis inhibit protein tyrosine phosphatase 1B. ( Bioorganic & Medicinal Chemistry Letters , 20 (2010), 7152 – 7154, *Corresponding author )

　　• Gao, Peng*; Li, Xiang * ; Cui, Dejun; Wu, Limin; Gruber, Margaret Y. Sk21 , a novel Arabidopsis seed coat mutant decreases the accumulation of flavonoid, anthocyanin and proanthocyanin content. ( Plant Biotechnology Journal , 8 (2010), 979 – 993 , *Co-first author)

　　• Li, Xiang ; Gao, Ming-jun; Pan, Hongyu; Cui, Dejun; Gruber, Margaret Y. Purple Canola- Arabidopsis PAP1 increases antioxidants and phenolics in Brassica napus leaves. ( Journal of Agricultural and Food Chemistry , (2010), 1639 – 1645)

　　• Huang, Jun; Bhinu, V. S.; Li, Xiang ; Dallal-Bashia, Zafer; Zhou, Rong; Hannoufa, Abdelali . Large-scale gene expression and targeted metabolite analysis reveal contrasting pleiotropic changes in Arabidopsis f5h and sct mutants grown under abiotic and biotic stresses. ( Planta , 230 (2009), 1057 – 1069)

　　• Wei, Shu*; Li, Xiang * ; Gruber, Margaret Y.; Li, Rong; Zhou, Rong; Zebarjadi, Alireza; Hannoufa, Abdelali . RNAi-mediated suppression of DET1 alters the levels of carotenoid and sinapate ester compounds in mature seeds of Brassica napus . ( Journal of Agricultural and Food Chemistry , 57 (2009), 5326 – 5333, *Co-first author)

　　• Li, Xiang ; Gao, Peng; Gruber, Margaret Y.; Neil, Westcott; Gjetvaj, Branimir. Analysis of the metabolome and transcriptome of Brassica carinata seedlings after lithium chloride exposure. ( Plant Science , 177 (2009), 68 – 80)

　　• Gao, Mingjun; Lydiate, Derek; Li, Xiang ; Lui, Helen; Gjetvaj, Branimir, Hegedus, Dwayne; Rozwadowski, Kevin. Repression of seed maturation genes by a trihelix transcriptional repressor in Arabidopsis seedlings. ( Plant Cell , 21 (2009), 54 – 71)

　　• Shubha, Maiya; Grundmann, Alexander; Li, Xiang ; Li, Shu-Ming; Geoffrey, Turner. Identification of a hybrid PKS /NRPS required for Pseurotin A biosynthesis in the human pathogen Aspergillus fumigates. (ChemBioChem, 8 (2007), 1736 – 1743)

　　• Xu, Minjuan; Gessner, Guido; Groth, Ingrid; Lange, Corinna; Christner, Arnulf; Bruhn, Torsten; Deng, Zhiwei; Li, Xiang ; Heinemann, Stefan; Grabley, Susanne; Bringmann, Gerhard; Sattler, Isabel; Lin, Wenhan. Shearinines D-K, new indole triterpenoids from an endophytic Penicillium sp. (Strain HKI0459) with blocking activity on large-conductance calcium-activated potassium channels. (Tetrahedron, 63 (2007), 435 – 444)

　　• Li, LiYa; Li, Xiang ; Shi, Cui; Deng, Zhiwei; Lin, Wenhan. Pongamone A-E, five flavonoids from the stems of a mangrove plant, Pongamia pinnata. (Phytochemistry, 67 (2006), 1347 – 1352)